The video is part of “Raccontare la ricerca“, the communication project, promoted by the University of Pisa in collaboration with Dipartimento di Civiltà e Forme del Sapere, which describes the main scientific projects promoted at the University of Pisa. The video tells about scientific studies concerning the development of molecules that can counteract the metabolism of cancer cells. For this purpose, in addition to the development of synthetic molecules, studies were also focused on natural compounds such as crocetin present in saffron.
Funded past projects as Principal Investigator:
- PRIN2017 (project code 2017SA5837) “Exploiting synergy in molecular targeted anticancer chemotherapy: synthesis, optimization, mechanism of action determination and biological validation in cellular and animal models of novel molecules targeting convergent metabolic pathways in cancer“
- FISM (2020/PR-Single/005) “Targeting the endocannabinoid system to fight multiple sclerosis: monoacylglycerol lipase degradation by PROTACs”
Funded ongoing project as Principal Investigator:
“Ricerca finalizzata” of Ministry of Health, section “Progetti Giovani Rircercatori, Theory Enhancing” (GR-2021-12374267) “The theranostic value of STARD3 in colorectal cancer”