{"id":6,"count":1,"description":"Syllabus\r\n\r\n1. Introduction to Neural Stem Cells (NSCs) and neurogenesis. How to build a brain. Historical perspective.\r\n\r\n2. Early neurogenesis in mammalian development: initial regional specification of NSCs; different types of NSCs. Neuroepithelial cells and radial glial cells. Early neurogenic phase and symmetric versus asymmetric divisions.\r\n\r\n3. Late neurogenesis in mammalian development: middle and late neurogenic phases, gliogenesis. Outer radial glia in human cortical development and evolution.\r\n\r\n4. Adult SVZ neurogenic niche: structure and definition of the NSC component.\r\n\r\n5. Physiological relevance of adult SVZ neurogenesis: olfactory neurons, relevance in human. Adult hippocampal SGZ neurogenic niche: structure and definition of the NSC component, rodent versus human. Physiological relevance of adult hippocampal neurogenesis.\r\n\r\n6. NSCs in vitro: tissue-derived systems, neurospheres and adherent cell culture.\r\n\r\n7. NSCs and neurogenesis in vitro: pluripotent stem cell-derived neural systems. Neural induction and directed neural differentiation.\r\n\r\n8. NSCs in disease: neurodevelopmental and neurodegenerative disorders.\r\n\r\n9. Brain tumors and tumor initiating cells.\r\n\r\n10. Regenerative approaches to the CNS: cell transplantation in Parkinson\u2019s disease, Huntington\u2019s disease, and spinal cord injury.\r\n\r\n11. Advanced 3D neural systems: retina and brain organoids.\r\n\r\n12. Direct reprogramming to neural fates.","link":"https:\/\/people.unipi.it\/marco_onorati\/category\/corsi\/neural-stem-cells\/","name":"Neural Stem Cells","slug":"neural-stem-cells","taxonomy":"category","parent":7,"meta":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neural Stem Cells Archivi - Marco Onorati<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/people.unipi.it\/marco_onorati\/category\/corsi\/neural-stem-cells\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neural Stem Cells Archivi - Marco Onorati\" \/>\n<meta property=\"og:description\" content=\"Syllabus 1. Introduction to Neural Stem Cells (NSCs) and neurogenesis. How to build a brain. Historical perspective. 2. Early neurogenesis in mammalian development: initial regional specification of NSCs; different types of NSCs. Neuroepithelial cells and radial glial cells. Early neurogenic phase and symmetric versus asymmetric divisions. 3. Late neurogenesis in mammalian development: middle and late neurogenic phases, gliogenesis. Outer radial glia in human cortical development and evolution. 4. Adult SVZ neurogenic niche: structure and definition of the NSC component. 5. Physiological relevance of adult SVZ neurogenesis: olfactory neurons, relevance in human. Adult hippocampal SGZ neurogenic niche: structure and definition of the NSC component, rodent versus human. Physiological relevance of adult hippocampal neurogenesis. 6. NSCs in vitro: tissue-derived systems, neurospheres and adherent cell culture. 7. NSCs and neurogenesis in vitro: pluripotent stem cell-derived neural systems. Neural induction and directed neural differentiation. 8. NSCs in disease: neurodevelopmental and neurodegenerative disorders. 9. Brain tumors and tumor initiating cells. 10. Regenerative approaches to the CNS: cell transplantation in Parkinson\u2019s disease, Huntington\u2019s disease, and spinal cord injury. 11. Advanced 3D neural systems: retina and brain organoids. 12. 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Introduction to Neural Stem Cells (NSCs) and neurogenesis. How to build a brain. Historical perspective. 2. Early neurogenesis in mammalian development: initial regional specification of NSCs; different types of NSCs. Neuroepithelial cells and radial glial cells. Early neurogenic phase and symmetric versus asymmetric divisions. 3. Late neurogenesis in mammalian development: middle and late neurogenic phases, gliogenesis. Outer radial glia in human cortical development and evolution. 4. Adult SVZ neurogenic niche: structure and definition of the NSC component. 5. Physiological relevance of adult SVZ neurogenesis: olfactory neurons, relevance in human. Adult hippocampal SGZ neurogenic niche: structure and definition of the NSC component, rodent versus human. Physiological relevance of adult hippocampal neurogenesis. 6. NSCs in vitro: tissue-derived systems, neurospheres and adherent cell culture. 7. NSCs and neurogenesis in vitro: pluripotent stem cell-derived neural systems. Neural induction and directed neural differentiation. 8. NSCs in disease: neurodevelopmental and neurodegenerative disorders. 9. Brain tumors and tumor initiating cells. 10. Regenerative approaches to the CNS: cell transplantation in Parkinson\u2019s disease, Huntington\u2019s disease, and spinal cord injury. 11. Advanced 3D neural systems: retina and brain organoids. 12. 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