{"id":2,"date":"2015-04-08T09:07:42","date_gmt":"2015-04-08T09:07:42","guid":{"rendered":"http:\/\/people.unipi.it\/cloner\/?page_id=2"},"modified":"2023-07-31T11:37:18","modified_gmt":"2023-07-31T09:37:18","slug":"home","status":"publish","type":"page","link":"https:\/\/people.unipi.it\/lorenzo_cangiano\/","title":{"rendered":"Home"},"content":{"rendered":"
\"profile<\/a>Lorenzo Cangiano, PhD<\/h5>\n
Associate Professor of Physiology<\/h5>\n

Dept. of Translational Research, University of Pisa<\/p>\n

E-mail: lorenzo.cangiano@unipi.it; Office: +39 0502213498; Cell: +39 3889253865<\/p>\n

Mailing address: Istituto di Fisiologia, Via San Zeno 31, 56123 Pisa, Italy<\/p>\n

Our research focuses on two independent areas of neuroscience: (i<\/em>) photoreceptor neurophysiology and therapeutic approaches to inherited retinal disesases; (ii<\/em>) the organization and function of the central pattern generator for ejaculation in the lumbar spinal cord.<\/p>\n

My lab has pioneered patch clamp electrophysiological recordings from rod and cone photoreceptors in the mouse retina, techniques now complemented by long duration in vitro electroretinography. We are available for scientific collaboration with research laboratories, as well as the pharmaceutical industry, who are interested in obtaining a functional assessment of the outer retina in (i) mouse models of retinal disease (ii) following pharmacological treatment, gene therapy or cell transplantation (iii) acute delivery of candidate drugs or new molecules under development.<\/p>\n

Recent and selected publications<\/strong><\/p>\n

Beelen CJ,  Asteriti S, Cangiano L<\/strong>, Koch K-W, Dell’Orco D (2021)
\nA hybrid stochastic\/deterministic model of single photon response and light adaptation in mouse rods. Computational and Structural Biotechnology Journal<\/em> (in press) link<\/a><\/p>\n

Cangiano L<\/strong>, Asteriti S (2021). Interphotoreceptor coupling: an evolutionary perspective. Pflugers Arch<\/em> (in press) link<\/a><\/p>\n

Asteriti S, Ricci V, Cangiano L<\/strong> (2020). Two simple criteria to estimate an objective’s performance when imaging in non design tissue clearing solutions. J Neurosci Methods<\/em> 332: 108564. link<\/a><\/p>\n

Federighi G, Asteriti S, Cangiano L<\/strong> (2019). Lumbar spinal cord neurons putatively involved in ejaculation are sexually dimorphic in early postnatal mice J Comp Neurol<\/i> 528: 624-36. link<\/a><\/p>\n

Asteriti S, Gargini C, Cangiano L<\/strong> (2017). Connexin 36 expression is required for electrical coupling between mouse rods and cones. Visual Neurosci<\/em> 34: e006. \"Access by Prof. Gordon Fain<\/a>   link<\/a><\/p>\n

Asteriti S, Grillner S, Cangiano L<\/b> (2015). A Cambrian origin for vertebrate rods. eLife<\/i> 4: e07166: 1\u201316. link<\/a><\/p>\n

Asteriti S, Gargini C, Cangiano L<\/b> (2014). Mouse rods signal through gap junctions with cones. eLife<\/i> 3: e01386: 1\u201321. link<\/a>\"Journal<\/a><\/p>\n

Cangiano L<\/b>, Asteriti S, Cervetto L, Gargini M (2012). The photovoltage of rods and cones in the dark-adapted mouse retina. J Physiol<\/i> 590: 3841\u201355. \"Journal<\/a><\/p>\n

<\/b>Mentel T, Cangiano L<\/b>, Grillner S, B\u00fcschges A (2008). Neuronal substrates for state-dependent changes in coordination between motoneuron pools during fictive locomotion in the lamprey spinal cord. J Neurosci<\/i> 28: 868\u201379.<\/p>\n

Cangiano L<\/b>, Grillner S (2005). Mechanisms of rhythm generation in a spinal locomotor network deprived of crossed connections: the lamprey hemicord. J Neurosci<\/i> 25: 923\u201335. \"Access by Prof. Ole Kiehn<\/a><\/p>\n

Cangiano L<\/b>, Grillner S (2003). Fast and slow locomotor burst generation in the hemi-spinal cord of the lamprey. J Neurophysiol<\/i> 89: 2931\u201342.<\/p>\n

<\/b>Buffelli M, Busetto G, Cangiano L<\/b>, Cangiano A (2002). Perinatal switch from synchronous to asynchronous activity of motoneurons: link with synapse elimination. Proc Natl Acad Sci USA<\/i> 99: 13200\u20135.<\/p>\n

Ongoing collaborations<\/strong><\/p>\n

Daniele Dell\u2019Orco, Dept. of Life and Reproduction Sciences, University of Verona, Italy<\/p>\n","protected":false},"excerpt":{"rendered":"

Lorenzo Cangiano, PhD Associate Professor of Physiology Dept. of Translational Research, University of Pisa E-mail: lorenzo.cangiano@unipi.it; Office: +39 0502213498; Cell: +39…<\/p>\n

Leggi tutto…<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/homepagefull.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-2","page","type-page","status-publish","hentry"],"acf":[],"featured_image_src":null,"yoast_head":"\nHome - Lorenzo Cangiano<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/people.unipi.it\/lorenzo_cangiano\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Home - Lorenzo Cangiano\" \/>\n<meta property=\"og:description\" content=\"Lorenzo Cangiano, PhD Associate Professor of Physiology Dept. of Translational Research, University of Pisa E-mail: lorenzo.cangiano@unipi.it; Office: +39 0502213498; Cell: +39…Leggi tutto...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/people.unipi.it\/lorenzo_cangiano\/\" \/>\n<meta property=\"og:site_name\" content=\"Lorenzo Cangiano\" \/>\n<meta property=\"article:modified_time\" content=\"2023-07-31T09:37:18+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/people.unipi.it\/lorenzo_cangiano\/wp-content\/uploads\/sites\/125\/2021\/06\/IMG_0215-150x150.jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/\",\"url\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/\",\"name\":\"Home - Lorenzo Cangiano\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/wp-content\\\/uploads\\\/sites\\\/125\\\/2021\\\/06\\\/IMG_0215-150x150.jpeg\",\"datePublished\":\"2015-04-08T09:07:42+00:00\",\"dateModified\":\"2023-07-31T09:37:18+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/#breadcrumb\"},\"inLanguage\":\"it-IT\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/#primaryimage\",\"url\":\"http:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/wp-content\\\/uploads\\\/sites\\\/125\\\/2021\\\/06\\\/IMG_0215-150x150.jpeg\",\"contentUrl\":\"http:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/wp-content\\\/uploads\\\/sites\\\/125\\\/2021\\\/06\\\/IMG_0215-150x150.jpeg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Home\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/#website\",\"url\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/\",\"name\":\"Lorenzo Cangiano\",\"description\":\"Universit\u00e0 di Pisa\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/people.unipi.it\\\/lorenzo_cangiano\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"it-IT\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Home - Lorenzo Cangiano","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/people.unipi.it\/lorenzo_cangiano\/","og_locale":"it_IT","og_type":"article","og_title":"Home - Lorenzo Cangiano","og_description":"Lorenzo Cangiano, PhD Associate Professor of Physiology Dept. of Translational Research, University of Pisa E-mail: lorenzo.cangiano@unipi.it; 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